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pentobarbital will reduce the level or result of etravirine by influencing hepatic enzyme CYP2C9/10 metabolism. Use Caution/Observe.pentobarbital will lessen the level or influence of cobimetinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Steer clear of coadministration. Powerful or reasonable CYP3A inducers may well